🎙️ podcast Analysis December 26, 2025 The a16z Show

The Infrastructure Insurgents: How Native-First Primitives Outflank Legacy Distribution

Crypto Infrastructure Lab Automation B2B Software
Conviction MEDIUM
Risk Profile 2.2/10 (MODERATE RISK)
Horizon 18-36 months
Signal Snapshot Core Theme: Infrastructure Primitives

Incumbents innovate to compete with AI-native startups

Build native-first solutions for underserved customer segments

Regulatory clarity; AI reasoning advances; Startup scaling

Executive Summary

A16z's investment team identifies three converging infrastructure primitives that bypass traditional distribution bottlenecks. Guy Willett argues stablecoins are narrow banks that must evolve into on-chain credit origination to scale beyond tokenized fiat, reducing loan servicing costs from 1-3% annually while enabling composability impossible in traditional finance. Oliver Shoe sees autonomous labs emerging through AI reasoning combined with robot learning, creating collaborative human-AI-robot...

Key Investment Opportunity

Native-First Financial Infrastructure

On-chain credit origination and synthetic dollar factories create scalable financial products with lower operational costs than tokenized traditional assets

...and 2 more investment opportunities

This is a preview. Log in to see the full analysis including investment opportunities, risks, catalysts, and detailed insights.


Next:
The Rejection Ritual: When Declining Suitors Reveals Strategic Desperation →

Warner Bros Discovery trades at $28.95, up 174% year-to-date, as management prepares to reject Paramount's unchanged…

Investment Disclaimer: StackAlpha provides information and analysis tools for educational purposes only. Nothing on this platform constitutes investment advice, and you should not rely solely on this information for investment decisions. Past performance does not guarantee future results. Always consult with qualified financial advisors before making investment decisions. Full Disclaimer